Determination of formaldehyde in textile dye and auxiliary chemicals with headspace gas chromatography-flame ionization detector

Determination of Residual Epichlorohydrin in Sevelamer Hydrochloride by Static Headspace Gas Chromatography with Flame Ionization Detection

A sensitive static headspace gas chromatographic method was developed and validated for the determination of residual epichlorohydrin (ECH) in sevelamer hydrochloride (SVH) drug substance. This method utilized a Phenomenex Zebron ZB-WAX GC column, helium as carrier gas with flame ionization detection. The critical experimental parameters, such as, headspace vial incubation time and incubation t...

Determination of Triethylamine, Pyridine and Dimethyl Formamide Content in Telmisartan by Headspace Gas Chromatography Using Flame Ionization Detector

Residual solvent determination by head space gas chromatography with flame ionization detector in omeprazole API

Residual solvents in pharmaceutical samples are monitored using gas chromatography with head space. Based on good manufacturing practices, measuring residual solvents is mandatory for the release testing of all active pharmaceutical ingredients (API). The analysis of residual organic solvents (methanol, acetone, cyclohexane, dichloromethane, toluene) in Omeprazole, an active pharmaceutical ingr...

Methane, Ethylene, and Ethane in Water by Headspace-Gas Chromatography with Flame Ionization Detection

The technology presents a number of environmental challenges as the wells are drilled vertically through aquifers on their way to the deep shale deposits thousands of feet under the surface, and then turned horizontally and drilled another several thousand feet through the shale deposit. Herein lies the challenge: in the process of drilling the wells and preparing them for production (including...

Identification of volatiles by headspace gas chromatography with simultaneous flame ionization and mass spectrometric detection.

Volatiles are frequently abused as inhalants. The methods used for identification are generally nonspecific if analyzed concurrently with ethanol or require an additional analytical procedure that employs mass spectrometry. A previously published technique utilizing a capillary flow technology splitter to simultaneously quantitate and confirm ethyl alcohol by flame ionization and mass spectrome...